Search on: GLUCAGON-LIKE PEPTIDE 1 
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Descriptor English:   Glucagon-Like Peptide 1 
Descriptor Spanish:   Péptido 1 Similar al Glucagón 
Descriptor Portuguese:   Peptídeo 1 Semelhante ao Glucagon 
Synonyms English:   GLP-1
Glucagon-Like Peptide-1
GLP 1
Glucagon Like Peptide 1  
Tree Number:   D06.472.317.469.500.500
Definition English:   A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake. 
Pharmacological Action:   Incretins
 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   50567 
Unique Identifier:   D052216 

Occurrence in VHL:
 

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